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Iron Oxide Nanoparticle-Induced Autophagic Flux Is Regulated by Interplay between p53-mTOR Axis and Bcl-2 Signaling in Hepatic Cells

Iron oxide-based nanoparticles have been repeatedly shown to affect lysosomal-mediated signaling. Recently, nanoparticles have demonstrated an ability to modulate autophagic flux via lysosome-dependent signaling. However, the precise underlying mechanisms of such modulation as well as the impact of...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Uzhytchak, Mariia, Smolková, Barbora, Lunova, Mariia, Jirsa, Milan, Frtús, Adam, Kubinová, Šárka, Dejneka, Alexandr, Lunov, Oleg
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226334/
https://ncbi.nlm.nih.gov/pubmed/32325714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9041015
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