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Nanoparticle core stability and surface functionalization drive the mTOR signaling pathway in hepatocellular cell lines

Specifically designed and functionalized nanoparticles hold great promise for biomedical applications. Yet, the applicability of nanoparticles is critically predetermined by their surface functionalization and biodegradability. Here we demonstrate that amino-functionalized polystyrene nanoparticles...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lunova, Mariia, Prokhorov, Andrey, Jirsa, Milan, Hof, Martin, Olżyńska, Agnieszka, Jurkiewicz, Piotr, Kubinová, Šárka, Lunov, Oleg, Dejneka, Alexandr
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700114/
https://ncbi.nlm.nih.gov/pubmed/29167516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16447-6
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