Retinal Tropism and Transduction of Adeno-Associated Virus Varies by Serotype and Route of Delivery (Intravitreal, Subretinal, or Suprachoroidal) in Rats

Viral-mediated gene augmentation offers tremendous promise for the treatment of inherited retinal diseases. The development of effective gene therapy requires an understanding of the vector's tissue-specific behavior, which may vary depending on serotype, route of delivery, or target species. U...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Gene Ther
Egile Nagusiak: Han, Ian C., Cheng, Justine L., Burnight, Erin R., Ralston, Christy L., Fick, Jessica L., Thomsen, Gabriella J., Tovar, Emilio F., Russell, Stephen R., Sohn, Elliott H., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A., Wiley, Luke A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc., publishers 2020
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757705/
https://ncbi.nlm.nih.gov/pubmed/32948113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.043
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