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CRISPR Arrays Away from cas Genes

CRISPR-Cas systems typically consist of a CRISPR array and cas genes that are organized in one or more operons. However, a substantial fraction of CRISPR arrays are not adjacent to cas genes. Definitive identification of such isolated CRISPR arrays runs into the problem of false-positives, with unre...

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Détails bibliographiques
Publié dans:CRISPR J
Auteurs principaux: Shmakov, Sergey A., Utkina, Irina, Wolf, Yuri I., Makarova, Kira S., Severinov, Konstantin V., Koonin, Eugene V.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc., publishers 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757702/
https://ncbi.nlm.nih.gov/pubmed/33346707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2020.0062
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