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Isolation, culture, and functional analysis of hepatocytes from mice with fatty liver disease

We present a protocol for isolating hepatocytes from mice with established non-alcoholic fatty liver disease. This protocol consists of liver perfusion using a peristaltic pump, followed by a modified 25% and 90% Percoll gradient centrifugation protocol to capture lipid-laden hepatocytes that are us...

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書目詳細資料
發表在:STAR Protoc
Main Authors: Jung, Yunshin, Zhao, Meng, Svensson, Katrin J.
格式: Artigo
語言:Inglês
出版: Elsevier 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757664/
https://ncbi.nlm.nih.gov/pubmed/33377114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100222
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