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Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
Polycystic ovary syndrome (PCOS), a metabolic and reproductive disease, is frequently associated with type 2 diabetes. We have demonstrated activating autoantibodies (AAb) directed toward the second extracellular loop (ECL2) of the gonadotropin‐releasing hormone receptor (GnRHR) are present in a sig...
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| 出版年: | Physiol Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7757370/ https://ncbi.nlm.nih.gov/pubmed/33356018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14672 |
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