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Elevated activity levels of activating autoantibodies to the GnRH receptor in patients with polycystic ovary syndrome

OBJECTIVES: 1) To confirm the correlation of GnRH receptor (GnRHR) activating autoantibody (AAb) activity with polycystic ovary syndrome (PCOS) diagnosis in large well defined cohorts; and 2) to evaluate suppression of AAb activity with GnRH antagonist medication in transfected GnRHR cells exposed t...

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Bibliografiske detaljer
Udgivet i:F S Rep
Main Authors: Weedin, Elizabeth A., Burks, Heather R., Yu, Xichun, Li, Hong Liang, Aston, Christopher E., Kem, David C., Craig, LaTasha B.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244267/
https://ncbi.nlm.nih.gov/pubmed/34223260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xfre.2020.09.015
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