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Eomesodermin in CD4(+)T cells is essential for Ginkgolide K ameliorating disease progression in experimental autoimmune encephalomyelitis
Eomesodermin (Eomes), a transcription factor, could suppress the Th17 cell differentiation and proliferation through directly binding to the promoter zone of the Rorc and Il17a gene, meanwhile the expression of Eomes is suppressed when c-Jun directly binds to its promoter zone. Ginkgolide K (1,10-di...
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| Publicat a: | Int J Biol Sci |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Ivyspring International Publisher
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7757039/ https://ncbi.nlm.nih.gov/pubmed/33390832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.50041 |
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