CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Primary Innate Immune Cells

CRISPR-Cas9 genome engineering can be used to functionally investigate the complex mechanisms of immune system regulation. Decades of work have aimed to genetically reprogram innate immunity, but current approaches are inefficient or nonspecific, limiting their use. Here, we detail an optimized stra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:STAR Protoc
Egile Nagusiak: Hildreth, Andrew D., Riggan, Luke, O’Sullivan, Timothy E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
Protocol
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756923/
https://ncbi.nlm.nih.gov/pubmed/33377009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100113
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