Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4

In stressed cells, phosphorylation of eukaryotic initiation factor 2α (eIF2α) controls transcriptome-wide changes in mRNA translation and gene expression known as the integrated stress response. We show here that DCs are characterized by high eIF2α phosphorylation, mostly caused by the activation of...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Mendes, Andreia, Gigan, Julien P, Rodriguez Rodrigues, Christian, Choteau, Sébastien A, Sanseau, Doriane, Barros, Daniela, Almeida, Catarina, Camosseto, Voahirana, Chasson, Lionel, Paton, Adrienne W, Paton, James C, Argüello, Rafael J, Lennon-Duménil, Ana-Maria, Gatti, Evelina, Pierre, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756897/
https://ncbi.nlm.nih.gov/pubmed/33443099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000865
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