Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4

In stressed cells, phosphorylation of eukaryotic initiation factor 2α (eIF2α) controls transcriptome-wide changes in mRNA translation and gene expression known as the integrated stress response. We show here that DCs are characterized by high eIF2α phosphorylation, mostly caused by the activation of...

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Veröffentlicht in:Life Sci Alliance
Hauptverfasser: Mendes, Andreia, Gigan, Julien P, Rodriguez Rodrigues, Christian, Choteau, Sébastien A, Sanseau, Doriane, Barros, Daniela, Almeida, Catarina, Camosseto, Voahirana, Chasson, Lionel, Paton, Adrienne W, Paton, James C, Argüello, Rafael J, Lennon-Duménil, Ana-Maria, Gatti, Evelina, Pierre, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Life Science Alliance LLC 2020
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756897/
https://ncbi.nlm.nih.gov/pubmed/33443099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000865
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