Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4

In stressed cells, phosphorylation of eukaryotic initiation factor 2α (eIF2α) controls transcriptome-wide changes in mRNA translation and gene expression known as the integrated stress response. We show here that DCs are characterized by high eIF2α phosphorylation, mostly caused by the activation of...

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Vydáno v:Life Sci Alliance
Hlavní autoři: Mendes, Andreia, Gigan, Julien P, Rodriguez Rodrigues, Christian, Choteau, Sébastien A, Sanseau, Doriane, Barros, Daniela, Almeida, Catarina, Camosseto, Voahirana, Chasson, Lionel, Paton, Adrienne W, Paton, James C, Argüello, Rafael J, Lennon-Duménil, Ana-Maria, Gatti, Evelina, Pierre, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: Life Science Alliance LLC 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756897/
https://ncbi.nlm.nih.gov/pubmed/33443099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000865
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