Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

OBJECTIVE: Microglial phagocytosis of apoptotic cells is an essential component of the brain regenerative response during neurodegeneration. Whereas it is very efficient in physiological conditions, it is impaired in mouse and human mesial temporal lobe epilepsy, and now we extend our studies to a m...

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Bibliografiske detaljer
Udgivet i:Epilepsia
Main Authors: Sierra‐Torre, Virginia, Plaza‐Zabala, Ainhoa, Bonifazi, Paolo, Abiega, Oihane, Díaz‐Aparicio, Irune, Tegelberg, Saara, Lehesjoki, Anna‐Elina, Valero, Jorge, Sierra, Amanda
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Full‐length Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756777/
https://ncbi.nlm.nih.gov/pubmed/32940364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.16692
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