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Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

OBJECTIVE: Microglial phagocytosis of apoptotic cells is an essential component of the brain regenerative response during neurodegeneration. Whereas it is very efficient in physiological conditions, it is impaired in mouse and human mesial temporal lobe epilepsy, and now we extend our studies to a m...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Sierra‐Torre, Virginia, Plaza‐Zabala, Ainhoa, Bonifazi, Paolo, Abiega, Oihane, Díaz‐Aparicio, Irune, Tegelberg, Saara, Lehesjoki, Anna‐Elina, Valero, Jorge, Sierra, Amanda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756777/
https://ncbi.nlm.nih.gov/pubmed/32940364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.16692
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