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Picky ABCG5/G8 and promiscuous ABCG2 ‐ a tale of fatty diets and drug toxicity
Structural data on ABCG5/G8 and ABCG2 reveal a unique molecular architecture for subfamily G ATP‐binding cassette (ABCG) transporters and disclose putative substrate‐binding sites. ABCG5/G8 and ABCG2 appear to use several unique structural motifs to execute transport, including the triple helical bu...
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7756502/ https://ncbi.nlm.nih.gov/pubmed/32978801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13938 |
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