A Stearoyl–Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α‐Synuclein Mice

OBJECTIVE: Parkinson disease (PD) has useful symptomatic treatments that do not slow the neurodegenerative process, and no significant disease‐modifying treatments are approved. A key therapeutic target in PD is α‐synuclein (αS), which is both genetically implicated and accumulates in Lewy bodies ri...

詳細記述

保存先:
書誌詳細
出版年:Ann Neurol
主要な著者: Nuber, Silke, Nam, Alice Y., Rajsombath, Molly M., Cirka, Haley, Hronowski, Xiaoping, Wang, Junmin, Hodgetts, Kevin, Kalinichenko, Liubov S., Müller, Christian P., Lambrecht, Vera, Winkler, Jürgen, Weihofen, Andreas, Imberdis, Thibaut, Dettmer, Ulf, Fanning, Saranna, Selkoe, Dennis J.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2020
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756464/
https://ncbi.nlm.nih.gov/pubmed/32996158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25920
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