Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2

Neuroendocrine prostate cancer (NEPC) is a more aggressive subtype of castration‐resistant prostate cancer (CRPC). Although it is well established that PHF8 can enhance prostate cancer cell proliferation, whether PHF8 is involved in prostate cancer initiation and progression is relatively unclear. B...

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Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Liu, Qiuli, Pang, Jian, Wang, Lin‐ang, Huang, Zhuowei, Xu, Jing, Yang, Xingxia, Xie, Qiubo, Huang, Yiqiang, Tang, Tang, Tong, Dali, Liu, Gaolei, Wang, Luofu, Zhang, Dianzheng, Ma, Qiang, Xiao, Hualiang, Lan, Weihua, Qin, Jun, Jiang, Jun
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2020
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756255/
https://ncbi.nlm.nih.gov/pubmed/33009820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5557
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