Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation

2,3-Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, we describe a method that enables direct access to these core structures from non-conjugated alkenyl amides and ortho-iodoanilines/phenols. Under palladium(II) catalysis this [3 + 2] heteroannula...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Ni, Hui-Qi, Kevlishvili, Ilia, Bedekar, Pranali G., Barber, Joyann S., Yang, Shouliang, Tran-Dubé, Michelle, Romine, Andrew M., Lu, Hou-Xiang, McAlpine, Indrawan J., Liu, Peng, Engle, Keary M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755910/
https://ncbi.nlm.nih.gov/pubmed/33353940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20182-4
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