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Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles
Small molecules containing cyclopropane–heteroatom linkages are commonly needed in medicinal chemistry campaigns, yet are problematic to prepare using existing methods. To address this issue, a scalable Chan–Lam cyclopropylation reaction using potassium cyclopropyl trifluoroborate has been developed...
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| Publicado no: | J Org Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003411/ https://ncbi.nlm.nih.gov/pubmed/29498847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b03100 |
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