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Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles
Small molecules containing cyclopropane–heteroatom linkages are commonly needed in medicinal chemistry campaigns, yet are problematic to prepare using existing methods. To address this issue, a scalable Chan–Lam cyclopropylation reaction using potassium cyclopropyl trifluoroborate has been developed...
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| 出版年: | J Org Chem |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003411/ https://ncbi.nlm.nih.gov/pubmed/29498847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b03100 |
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