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Reduction in flippase activity contributes to surface presentation of phosphatidylserine in human senescent erythrocytes

Mature human erythrocytes circulate in blood for approximately 120 days, and senescent erythrocytes are removed by splenic macrophages. During this process, the cell membranes of senescent erythrocytes express phosphatidylserine, which is recognized as a signal for phagocytosis by macrophages. Howev...

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Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: Seki, Momoko, Arashiki, Nobuto, Takakuwa, Yuichi, Nitta, Kosaku, Nakamura, Fumio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754070/
https://ncbi.nlm.nih.gov/pubmed/33103382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16010
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