In silico and in vitro insights into tyrosinase inhibitors with a 2-thioxooxazoline-4-one template

The β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold confers tyrosinase inhibitory activity, and in the present study, 16 (Z)-5-(substituted benzylidene)-3-phenyl-2-thioxooxazolidin-4-one analogues containing this scaffold were synthesized. Mushroom tyrosinase inhibitory activities were examined. C...

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Bibliographic Details
Published in:Comput Struct Biotechnol J
Main Authors: Choi, Inkyu, Park, Yujin, Ryu, Il Young, Jung, Hee Jin, Ullah, Sultan, Choi, Heejeong, Park, Chaeun, Kang, Dongwan, Lee, Sanggwon, Chun, Pusoon, Young Chung, Hae, Moon, Hyung Ryong
Format: Artigo
Language:Inglês
Published: Research Network of Computational and Structural Biotechnology 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753086/
https://ncbi.nlm.nih.gov/pubmed/33363708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.12.001
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