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(11)C-UCB-J synaptic PET and multimodal imaging in dementia with Lewy bodies

OBJECTIVE: Dementia with Lewy bodies (DLB) is a common cause of dementia, but atrophy is mild compared to Alzheimer’s disease. We propose that DLB is associated instead with severe synaptic loss, and we test this hypothesis in vivo using positron emission tomography (PET) imaging of (11)C-UCB-J, a l...

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Bibliografiske detaljer
Udgivet i:Eur J Hybrid Imaging
Main Authors: Nicastro, Nicolas, Holland, Negin, Savulich, George, Carter, Stephen F., Mak, Elijah, Hong, Young T., Milicevic Sephton, Selena, Fryer, Tim D., Aigbirhio, Franklin I., Rowe, James B., O’Brien, John T.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752786/
https://ncbi.nlm.nih.gov/pubmed/33381679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41824-020-00093-9
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