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Critical effect of Pol escape mutations associated with detrimental allele HLA-C(∗)15:05 on clinical outcome in HIV-1 subtype A/E infection
The mechanism explaining the role of detrimental HLA alleles in HIV-1 infections has been investigated in very few studies. HLA-A∗29:01-B∗07:05-C∗15:05 is a detrimental haplotype in HIV-1 subtype A/E-infected Vietnamese individuals. The accumulation of mutations at Pol 653/657 is associated with a p...
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| Udgivet i: | AIDS |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Lippincott Williams & Wilkins
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7752225/ https://ncbi.nlm.nih.gov/pubmed/33031103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002704 |
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