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The development of proteinase-activated receptor-2 modulators and the challenges involved

Protease-activated receptor-2 (PAR2) has been extensively studied since its discovery in the mid-1990. Despite the advances in understanding PAR2 pharmacology, it has taken almost 25 years for the first inhibitor to reach clinical trials, and so far, no PAR2 antagonist has been approved for human us...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochem Soc Trans
Päätekijät: McIntosh, Kathryn A., Cunningham, Margaret R., Bushell, Trevor, Plevin, Robin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Portland Press Ltd. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752072/
https://ncbi.nlm.nih.gov/pubmed/33242065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20200191
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