The development of proteinase-activated receptor-2 modulators and the challenges involved

Protease-activated receptor-2 (PAR2) has been extensively studied since its discovery in the mid-1990. Despite the advances in understanding PAR2 pharmacology, it has taken almost 25 years for the first inhibitor to reach clinical trials, and so far, no PAR2 antagonist has been approved for human us...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem Soc Trans
Prif Awduron: McIntosh, Kathryn A., Cunningham, Margaret R., Bushell, Trevor, Plevin, Robin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2020
Pynciau:
Review Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752072/
https://ncbi.nlm.nih.gov/pubmed/33242065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20200191
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