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Botulinum Neurotoxins A, B, C, E, and F preferentially enter cultured human motor neurons compared to other cultured human neuronal populations

Human induced pluripotent stem cell (hiPSC)-derived neurons can be exquisitely sensitive to botulinum neurotoxins (BoNTs), exceeding sensitivity of the traditionally used mouse bioassay. In this report, four defined hiPSC-derived neuronal populations including primarily GABAergic, glutamatergic, dop...

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Detalles Bibliográficos
Publicado en:FEBS Lett
Main Authors: Pellett, Sabine, Tepp, William H., Johnson, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751886/
https://ncbi.nlm.nih.gov/pubmed/31240706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13508
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