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Botulinum Neurotoxins Can Enter Cultured Neurons Independent of Synaptic Vesicle Recycling

Botulinum neurotoxins (BoNTs) are the causative agent of the severe and long-lasting disease botulism. At least seven different serotypes of BoNTs (denoted A-G) have been described. All BoNTs enter human or animal neuronal cells via receptor mediated endocytosis and cleave cytosolic SNARE proteins,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pellett, Sabine, Tepp, William H., Scherf, Jacob M., Johnson, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514655/
https://ncbi.nlm.nih.gov/pubmed/26207366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133737
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