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UBE2N Regulates Paclitaxel Sensitivity of Ovarian Cancer via Fos/P53 Axis

BACKGROUND: Chemo-resistance is still considered one of the key factors in the mortality of ovarian cancer. In this work, we found that ubiquitin-conjugating enzyme E2 N (UBE2N) is downregulated in paclitaxel-resistant ovarian cancer cells. It suggests UBE2N to be critical in the regulation of pacli...

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Publicado en:Onco Targets Ther
Main Authors: Zhu, Qiuyuan, Chen, Jieyuan, Pan, Peipei, Lin, Feng, Zhang, Xu
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751838/
https://ncbi.nlm.nih.gov/pubmed/33363381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S271164
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