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Macrophage mitochondrial MFN2 (mitofusin 2) links immune stress and immune response through reactive oxygen species (ROS) production

MFN2 (mitofusin 2) is required for mitochondrial fusion and for mitochondria-endoplasmic reticulum interaction. Using myeloid-conditional KO mice models, we found that MFN2 but not MFN1 is a prerequisite for the adaptation of mitochondrial respiration to stress conditions as well as for the producti...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Lloberas, Jorge, Muñoz, Juan P., Hernández-Álvarez, María Isabel, Cardona, Pere-Joan, Zorzano, Antonio, Celada, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751645/
https://ncbi.nlm.nih.gov/pubmed/33171058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1839191
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