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Structural Modeling of Wild and Mutant Forms of Human Plasma Platelet Activating Factor-Acetyl Hydrolase Enzyme

PURPOSE: To investigate the structural features of wild and mutant forms of the pPAF-AH enzyme that are responsible for coronary artery disease. METHODS: Mutant variants of human pPAF-AH having either V279F, Q281R, or both were modelled and evaluated for stereo chemical and structural correctness. T...

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Pubblicato in:J Inflamm Res
Autori principali: Khan, Mohd Imran, Hariprasad, Gururao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751442/
https://ncbi.nlm.nih.gov/pubmed/33364808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S274940
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