Oxygen radicals inhibit human plasma acetylhydrolase, the enzyme that catabolizes platelet-activating factor.

Platelet-activating factor (PAF) can exert profound inflammatory effects at very low concentrations. In plasma, PAF is hydrolyzed to lyso-PAF by acetylhydrolase, an enzyme that circulates bound to LDL. Previous studies suggest that oxygen radicals may act synergistically with PAF to potentiate tissu...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Ambrosio, G, Oriente, A, Napoli, C, Palumbo, G, Chiariello, P, Marone, G, Condorelli, M, Chiariello, M, Triggiani, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294448/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117248
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