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Efficient toolkit implementing best practices for principal component analysis of population genetic data

MOTIVATION: Principal component analysis (PCA) of genetic data is routinely used to infer ancestry and control for population structure in various genetic analyses. However, conducting PCA analyses can be complicated and has several potential pitfalls. These pitfalls include (i) capturing linkage di...

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Vydáno v:Bioinformatics
Hlavní autoři: Privé, Florian, Luu, Keurcien, Blum, Michael G B, McGrath, John J, Vilhjálmsson, Bjarni J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750941/
https://ncbi.nlm.nih.gov/pubmed/32415959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa520
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