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Detecting Genomic Signatures of Natural Selection with Principal Component Analysis: Application to the 1000 Genomes Data

To characterize natural selection, various analytical methods for detecting candidate genomic regions have been developed. We propose to perform genome-wide scans of natural selection using principal component analysis (PCA). We show that the common F(ST) index of genetic differentiation between pop...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Duforet-Frebourg, Nicolas, Luu, Keurcien, Laval, Guillaume, Bazin, Eric, Blum, Michael G.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776707/
https://ncbi.nlm.nih.gov/pubmed/26715629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv334
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