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Cross-Electrophile Coupling of Unactivated Alkyl Chlorides

Alkyl chlorides are bench-stable chemical feed-stocks that remain among the most underutilized electrophile classes in transition metal catalysis. Overcoming intrinsic limitations of C(sp(3))–Cl bond activation, we report the development of a novel organosilane reagent that can participate in chlori...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Sakai, Holt A., Liu, Wei, Le, Chi “Chip”, MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750884/
https://ncbi.nlm.nih.gov/pubmed/32564602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c04812
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