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Selective sp(3) C–H alkylation via polarity-match-based cross-coupling
The functionalization of carbon–hydrogen (C–H) bonds is one of the most attractive strategies for molecular construction in organic chemistry. The hydrogen atom is considered to be an ideal coupling handle, owing to its relative abundance in organic molecules and its availability for functionalizati...
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| Published in: | Nature |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655994/ https://ncbi.nlm.nih.gov/pubmed/28636596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22813 |
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