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Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Chlorides with Primary Alkyl Chlorides

Alkyl chlorides and aryl chlorides are among the most abundant and stable carbon electrophiles. Although their coupling with carbon nucleophiles is well developed, the cross-electrophile coupling of aryl chlorides with alkyl chlorides has remained a challenge. We report here the first general approa...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Kim, Seoyoung, Goldfogel, Matthew J., Gilbert, Michael M., Weix, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418462/
https://ncbi.nlm.nih.gov/pubmed/32412241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c02673
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