Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling

[Image: see text] Despite their importance, the synthesis of alkylated heterocycles from the cross-coupling of Lewis basic nitrogen heteroaryl halides with alkyl halides remains a challenge. We report here a general solution to this challenge enabled by a new collection of ligands based around 2-pyr...

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Bibliographic Details
Published in:J Org Chem
Main Authors: Hansen, Eric C., Li, Changfeng, Yang, Sihang, Pedro, Dylan, Weix, Daniel J.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2017
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539790/
https://ncbi.nlm.nih.gov/pubmed/28682073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b01334
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