A novel nitroalkene vitamin E analogue inhibits the NLRP3 inflammasome and protects against inflammation and glucose intolerance triggered by obesity

Chronic metabolic diseases, like obesity, type II diabetes and atherosclerosis often involve a low-grade and sterile systemic inflammatory state, in which activation of the pro-inflammatory transcription factor NF-kB and the NLRP3 inflammasome play a major role. It is well established that genetic i...

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Publicado no:Redox Biol
Main Authors: Dapueto, Rosina, Rodriguez-Duarte, Jorge, Galliussi, Germán, Kamaid, Andrés, Bresque, Mariana, Batthyány, Carlos, López, Gloria V., Escande, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750735/
https://ncbi.nlm.nih.gov/pubmed/33352465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101833
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