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Genetic background influences the impact of KLOTHO deficiency
Genetic background is a key but sometimes overlooked factor that profoundly impacts disease susceptibility and presentation in both humans and disease models. Here we show that deficiency of KLOTHO protein, an important renal regulator of mineral homeostasis and a cofactor for FGF23, causes differen...
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| Publicado no: | Physiol Genomics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7750509/ https://ncbi.nlm.nih.gov/pubmed/32956023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00094.2020 |
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