Determining homologous recombination deficiency scores with whole exome sequencing and their association with responses to neoadjuvant chemotherapy in breast cancer

Recent studies demonstrated that homologous repair deficiency (HRD) score is a useful marker for response to poly (ADP-ribose) polymerase inhibitors or platinum-based chemotherapy. We determined HRD scores and elucidated the clinicopathologic characteristics of HRD-high tumors and their response to...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Transl Oncol
Hoofdauteurs: Kim, Seung Jin, Sota, Yoshiaki, Naoi, Yasuto, Honma, Keiichiro, Kagara, Naofumi, Miyake, Tomohiro, Shimoda, Masafumi, Tanei, Tomonori, Seno, Shigeto, Matsuda, Hideo, Noguchi, Shinzaburo, Shimazu, Kenzo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press 2020
Onderwerpen:
Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750421/
https://ncbi.nlm.nih.gov/pubmed/33340887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100986
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items