Molecular Barcode Sequencing of the Whole Ligand Binding Domain of the ESR1 Gene in Cell-Free DNA from Patients with Metastatic Breast Cancer()

ESR1 mutations in breast cancer are known as one of the mechanisms of resistance to aromatase inhibitors. These mutations often occur in the hotspot regions in the ligand binding domain (LBD), but comprehensive mutational analysis has shown that mutations are observed throughout the whole LBD. We pr...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Masunaga, Nanae, Kagara, Naofumi, Motooka, Daisuke, Nakamura, Shota, Miyake, Tomohiro, Tanei, Tomonori, Naoi, Yasuto, Shimoda, Masafumi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2020
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042480/
https://ncbi.nlm.nih.gov/pubmed/32105989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.12.007
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