Molecular Barcode Sequencing of the Whole Ligand Binding Domain of the ESR1 Gene in Cell-Free DNA from Patients with Metastatic Breast Cancer()

ESR1 mutations in breast cancer are known as one of the mechanisms of resistance to aromatase inhibitors. These mutations often occur in the hotspot regions in the ligand binding domain (LBD), but comprehensive mutational analysis has shown that mutations are observed throughout the whole LBD. We pr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Transl Oncol
Hlavní autoři: Masunaga, Nanae, Kagara, Naofumi, Motooka, Daisuke, Nakamura, Shota, Miyake, Tomohiro, Tanei, Tomonori, Naoi, Yasuto, Shimoda, Masafumi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2020
Témata:
Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042480/
https://ncbi.nlm.nih.gov/pubmed/32105989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.12.007
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky