Molecular Barcode Sequencing of the Whole Ligand Binding Domain of the ESR1 Gene in Cell-Free DNA from Patients with Metastatic Breast Cancer()

ESR1 mutations in breast cancer are known as one of the mechanisms of resistance to aromatase inhibitors. These mutations often occur in the hotspot regions in the ligand binding domain (LBD), but comprehensive mutational analysis has shown that mutations are observed throughout the whole LBD. We pr...

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Masunaga, Nanae, Kagara, Naofumi, Motooka, Daisuke, Nakamura, Shota, Miyake, Tomohiro, Tanei, Tomonori, Naoi, Yasuto, Shimoda, Masafumi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2020
Fag:
Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042480/
https://ncbi.nlm.nih.gov/pubmed/32105989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.12.007
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