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Measurement of Cyclin D2 (CCND2) Gene Promoter Methylation in Plasma and Peripheral Blood Mononuclear Cells and Alpha-Fetoprotein Levels in Patients with Hepatitis B Virus-Associated Hepatocellular Carcinoma

BACKGROUND: Alpha-fetoprotein (AFP) is widely used to screen for hepatocellular carcinoma (HCC). However, the use of this biomarker has been challenged due to its low sensitivity and high rate of false negatives. In this study, we evaluated the diagnostic capability of cyclin D2 (CCND2) promoter met...

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Publicat a:Med Sci Monit
Autors principals: Qian, Yu, Wang, Jing-Wen, Yu-Fang, Yuan, Xiao-Dong, Fan, Yu-Chen, Gao, Shuai, Wang, Kai
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749526/
https://ncbi.nlm.nih.gov/pubmed/33320844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.927444
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