The Silencing of CCND2 by Promoter Aberrant Methylation in Renal Cell Cancer and Analysis of the Correlation between CCND2 Methylation Status and Clinical Features

Cyclin D2 (CCND2) is a member of the D-type cyclins, which plays a pivotal role in cell cycle regulation, differentiation and malignant transformation. However, its expression status and relative regulation mechanism remains unclear in renal cell cancer (RCC). In our study, the mRNA expression level...

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Udgivet i:PLoS One
Main Authors: Wang, Lu, Cui, Yun, Zhang, Lian, Sheng, Jindong, Yang, Yang, Kuang, Guanyu, Fan, Yu, Zhang, Qian, Jin, Jie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008725/
https://ncbi.nlm.nih.gov/pubmed/27583477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161859
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