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Measurement of Cyclin D2 (CCND2) Gene Promoter Methylation in Plasma and Peripheral Blood Mononuclear Cells and Alpha-Fetoprotein Levels in Patients with Hepatitis B Virus-Associated Hepatocellular Carcinoma

BACKGROUND: Alpha-fetoprotein (AFP) is widely used to screen for hepatocellular carcinoma (HCC). However, the use of this biomarker has been challenged due to its low sensitivity and high rate of false negatives. In this study, we evaluated the diagnostic capability of cyclin D2 (CCND2) promoter met...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Qian, Yu, Wang, Jing-Wen, Yu-Fang, Yuan, Xiao-Dong, Fan, Yu-Chen, Gao, Shuai, Wang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749526/
https://ncbi.nlm.nih.gov/pubmed/33320844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.927444
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