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Inverse correlation between fatty acid transport protein 4 and vision in Leber congenital amaurosis associated with RPE65 mutation

Fatty acid transport protein 4 (FATP4), a transmembrane protein in the endoplasmic reticulum (ER), is a recently identified negative regulator of the ER-associated retinal pigment epithelium (RPE)65 isomerase necessary for recycling 11-cis-retinal, the light-sensitive chromophore of both rod and con...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Songhua, Gordon, William C., Bazan, Nicolas G., Jin, Minghao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749325/
https://ncbi.nlm.nih.gov/pubmed/33257550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012623117
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