Prolonged administration of maraviroc reactivates latent HIV in vivo but it does not prevent antiretroviral-free viral rebound

Human immunodeficiency virus (HIV) remains incurable due to latent viral reservoirs established in non-activated CD4 T cells that cannot be eliminated via antiretroviral therapy. Current efforts to cure HIV are focused on identifying drugs that will induce viral gene expression in latently infected...

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Bibliographic Details
Published in:Sci Rep
Main Authors: López-Huertas, María Rosa, Gutiérrez, Carolina, Madrid-Elena, Nadia, Hernández-Novoa, Beatriz, Olalla-Sierra, Julián, Plana, Montserrat, Delgado, Rafael, Rubio, Rafael, Muñoz-Fernández, María Ángeles, Moreno, Santiago
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749169/
https://ncbi.nlm.nih.gov/pubmed/33339855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79002-w
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