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Submolecular probing of the complement C5a receptor–ligand binding reveals a cooperative two-site binding mechanism
A current challenge to produce effective therapeutics is to accurately determine the location of the ligand-biding site and to characterize its properties. So far, the mechanisms underlying the functional activation of cell surface receptors by ligands with a complex binding mechanism remain poorly...
Gorde:
| Argitaratua izan da: | Commun Biol |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749166/ https://ncbi.nlm.nih.gov/pubmed/33339958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01518-8 |
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