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DETERMINANTS OF LIGAND BINDING AFFINITY AND COOPERATIVITY AT THE GLUT1 ENDOFACIAL SITE

Cytochalasin B (CB) and forskolin (FSK) inhibit GLUT1-mediated sugar transport in red cells by binding at or close to the GLUT1 endofacial sugar binding site. Paradoxically, very low concentrations of each of these inhibitors produce a modest stimulation of sugar transport (Cloherty, E. K., Levine,...

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Detalhes bibliográficos
Main Authors: Robichaud, Trista, Appleyard, Antony N., Herbert, Richard B., Henderson, Peter J.F., Carruthers, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465710/
https://ncbi.nlm.nih.gov/pubmed/21384913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1020327
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